Nomograms of Rose et al for Locally Advanced Cervical Cancer: Prediction of Pelvic Recurrence

Description

Rose et al developed nomograms for evaluating women with locally advanced cervical cancer. One nomogram predicts the probability of pelvic recurrence. The authors are from multiple hospitals in the United States and Canada.

Patient selection: woman with locally advanced cervical cancer, age 20 to 85 years, ECOG performance status 0 to 3, tumor size 1 to 25 cm in diameter

Parameters:

(1) age of the patient in years

(2) histology

(3) performance status

(4) tumor size in cm

(5) FIGO stage

(6) pelvic lymph nodes

(7) treatment

points for age =

= (-0.2477 * (age)) + 21.054

Tumor Size	Points
<= 10 cm	(-0.2467 * ((diameter)^2)) + (4.755 * (diameter)) - 3.754
10 to 25 cm	(0.5067 * (diameter)) + 14.133

Parameter	Finding	Points
histology	squamous	0
	adenocarcinoma	3.3
	adenosquamous	3.3
performance status	0	0
	1	1.2
	2 or 3	7.9
FIGO stage	IB	72.2
	IIA	0
	IIB	83.5
	IIIA	100
	IIIB	90.8
	IVA	98.6
pelvic lymph nodes	negative or unknown	0
	positive	4.4
treatment	cisplatin plus radiation	0
	other chemotherapy plus radiation	8.8

total score =

= SUM(points for all 7 parameters)

Interpretation:

• minimum score: 0

• maximum score: 167

• The higher the score the greater the risk of pelvic recurrence.

Score	Probability of Pelvic Recurrence
< 104	< 10%
104 to 142	(0.01749 * ((points)^2)) - (2.586 * (points)) + 89.8
> 142	> 80%

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Description

Specialty

ICD-10