Nomograms of Raut et al for Retroperitoneal Sarcoma: Overall Survival (OS)

Description

Raut et al developed two nomograms for patients with a retroperitoneal sarcoma. One of these nomograms predicts overall survival. The authors are from multiple institutions in the North America and Europe.

Patient selection: retroperitoneal sarcoma, from 10 to 90 years of age

Outcome: 7-year overall survival (OS)

Parameters:

(1) tumor diameter in centimeters

(2) FNCLCC grade

(3) histologic subtype

(4) multifocality

(5) age

(6) extent of resection

Tumor Diameter	Points
0 to 20 cm	(-0.037635 * ((size)^2)) + (3.3559 * (size)) - 0.60102
20 to 30 cm	(0.392 * (size)) + 43.12
30 to 80 cm	(-0.0006125 * ((size)^2)) - (0.075425 * (size)) + 57.76

Age in Years	Points
10 to 50 years	(-0.37255 * (years)) + 18.373
50 to 60 years	(0.29412 * (years)) - 14.706
60 to 90 years	(1.1001 * (years)) - 63.954

Parameter	Finding	Points
FNCLCC grade	Grade 1	0
	Grade 2	74.5
	Grade 3	100
histologic subtype	solitary fibrous tumor	0
	malignant peripheral nerve sheath tumor	5.9
	liposarcoma, dedifferentiated	7.8
	leiomyosarcoma	20
	liposarcoma, well-differentiated	41.2
	unclassified, undifferentiated pleomorphic	25.5
	other	21.6
multifocal	no (unifocal)	0
	yes	26.5
extent of resection	complete	0
	incomplete	16.7

total score =

= SUM(points for all 6 parameters)

Interpretation:

• minimum score: 0

• maximum score: 275.3

Total Score	7-year overall survival
< 19.4	> 99%%
19.4 to 206	see X below
> 206	< 1%

X =

= (-0.000001806 * ((score)^3)) + (0.00045265 * ((score)^2)) - (0.065888 * (score)) + 5.764

probability =

= 1 / (1 + EXP((-1) * X))

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Nomograms of Raut et al for Retroperitoneal Sarcoma: Overall Survival (OS)

Description

Specialty