Nomograms of Raut et al for Retroperitoneal Sarcoma: Disease-Free Survival (DFS)

Description

Raut et al developed two nomograms for patients with a retroperitoneal sarcoma. One of these nomograms predicts disease-free survival. The authors are from multiple institutions in the North America and Europe.

Patient selection: retroperitoneal sarcoma

Outcome: 7-year disease-free survival (DFS)

Parameters:

(1) tumor diameter in centimeters

(2) FNCLCC grade

(3) histologic subtype

(4) multifocality

Tumor Diameter	Points
0 to 20 cm	(-0.037293 * ((size)^2)) + (3.0067 * (size)) - 0.5181
20 to 30 cm	(0.4704 * (size)) + 35.868
30 to 80 cm	53.821 - (0.1218 * (size))

Parameter	Finding	Points
FNCLCC grade	Grade 1	0
	Grade 2	61.7
	Grade 3	100
histologic subtype	solitary fibrous tumor	0
	malignant peripheral nerve sheath tumor	0.1
	liposarcoma, dedifferentiated	28
	leiomyosarcoma	40
	liposarcoma, well-differentiated	50
	unclassified, undifferentiated pleomorphic	42
	other	31
multifocal	no (unifocal)	0
	yes	46.6

total score =

= SUM(points for all 4 parameters)

Interpretation:

• minimum score: 0

• maximum score: 246.6

Total Score	7-year disease-free survival
< 4.7	> 95%
4.7 to 212	see X below
> 212	< 1%

X =

= (-0.00000094416 * ((score)^3)) + (0.00019188 * ((score)^2)) - (0.034428 * (score)) + 3.1601

probability =

= 1 / (1 + EXP((-1) * X))

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Nomograms of Raut et al for Retroperitoneal Sarcoma: Disease-Free Survival (DFS)

Description

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