Nomograms of He et al for Survival of a Patient with Periampullary Adenocarcinoma: Progression-Free Survival

Description

He et al reported two nomograms for patients with a periampullary adenocarcinoma who have undergone pancreatoduodenectomy. One model predicts progression-free survival. The authors are from Sun Yat-Sen Cancer Center in Guangzhou, China.

Patient selection: periampullary adenocarcinoma status post pancreatoduodenectomy

Parameters:

(1) lymph node ratio (LNR)

(2) type of tumor

(3) serum CA 19-9 concentration in U/mL

(4) tumor differentiation

Parameter	Finding	Points
LNR	< 0.17	0
	>= 0.17	7.24
type of tumor	duodenal	4.7
	ampullary	0
	pancreatic	10
CA 19-9	< 35 U/mL	0
	>= 35 U/mL	7.15
tumor differentiation	well-differentiated	0
	well-to-moderately	0.33
	moderately	0.71
	moderately-to-poor	3.86
	poorly differentiated	7.15

total score =

= SUM(points for all 4 parameters)

Interpretation:

• minimum score: 0

• maximum score: 31.54

Score	2-Year Progression-Free Survival
< 3.78	> 85%
3.78 to 29.96	(-0.0004135 * ((score)^2)) - (0.011376 * (score)) + 0.90397
> 29.96	< 20%

Performance:

• The area under the ROC curve is 0.68.

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Nomograms of He et al for Survival of a Patient with Periampullary Adenocarcinoma: Progression-Free Survival

Description

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