Fakhry et al reported 2 nomograms for predicting outcomes for a patient with oropharyngeal cancer. One model predicts overall survival. The authors are from Johns Hopkins University.
Patient selection: oropharyngeal cancer, ECOG 0 or 1
Parameters:
(1) age in years
(2) number of pack years for cigarette smoking
(3) p16 status
(4) T stage (T2, T3, T4)
(5) N stage (AJCC 8th edition)
(6) Zubrod/ECOG performance status (0 or 1)
(7) education
(8) anemia
Parameter
Finding
Points
age and pack years
<= 50 years old and <= 10 pack years
0
> 50 years old and <= 10 pack years
88.6
<= 50 years old and > 10 pack years
78.2
> 50 years old and > 10 pack years
100
p16 status
positive
0
negative
41
T stage
T2 or T3
0
T4
30.2
N stage
N0 or N1
0
N2 or N3
28
Zubrod PS
0
0
1
23.8
education
high school or less
27.7
post high school
0
anemia
no
0
yes
18.8
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 358
• The higher the score the worse the overall survival.
