Nomograms of Duan et al for Esophageal Squamous Cell Carcinoma: Overall Survival

Description

Duan et al reported two nomograms for patients with squamous cell carcinoma of the esophagus treated with esophagectomy and adjuvant chemotherapy. One nomogram predicts overall survival (OS). The authors are from Tianjin University Cancer Institute and Hospital and Tianjin Key Laboratory of Cancer Prevention and Therapy in China.

Patient selection: squamous cell carcinoma of the esophagus status post esophagectomy

Parameters:

(1) gender

(2) tumor length in cm, from 0 to 14 cm

(3) T status

(4) N status

(5) number of chemotherapy cycles

points for tumor length =

= 6.25 * (length in cm)

Parameter	Finding	Points
gender	female	0
	male	37.5
T status	T1a	0
	T1b	4.5
	T2	56.2
	T3	76.8
	T4a	100
N status	N0	0
	N1	37.6
	N2	62.3
	N3	80.7
chemotherapy cycles	>= 4	0
	1 to 3	33.3
	none	57.1

total score =

= SUM(points for all 5 parameters)

Interpretation:

• minimum score: 0

• maximum score: 362.8

Score	3-Year Overall Survival
< 93.7	> 90%
50.5 to 209.9	(-0.0000129 * ((score)^2)) + (0.0002575 * (score)) + 1.0019
> 278.1	< 10%

Performance:

• The area under the ROC curve is 0.71.

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Nomograms of Duan et al for Esophageal Squamous Cell Carcinoma: Overall Survival

Description

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