Nomogram of Zhang et al for Predicting Postoperative Recurrence in a Patient with Stage Ia Non-Small Cell Lung Carcinoma (NSCLC)

Description

Zhang et al developed a clinicopathologic model and nomogram for predicting postoperative recurrence in a patient with Stage Ia non-small cell lung cancer (NSCLC). This can help to identify a patient who may benefit from more aggressive management. The authors are from Fudan University Shanghai Cancer Center in China.

Patient selection: Stage Ia non-small cell lung cancer

Outcome: 3 year recurrence-free survival

Parameters:

(1) location

(2) T stage

(3) histologic grade (high grade = large cell carcinoma, solid predominant, micropapillary adenocarcinoma)

(4) differentiation

(5) lymphovascular invasion

Parameter	Finding	Points
location	peripheral	0
	central	83.4
T stage	T1a	0
	T1b	78
histologic grade	low-grade	0
	high-grade	100
differentiation	well-differentiated	0
	moderately differentiated	0
	poorly differentiated	67
lymphovascular invasion	none	0
	present	79

total score =

= SUM(points for all 5 parameters)

Interpretation:

• minimum score: 0

• maximum score: 427.4

• The higher the score the worse the prognosis.

Score	Probability of 3-Year Recurrence-Free Survival
< 39	> 90%
39 to 207.6	(-0.000882 * ((points)^2)) - (0.01891 * (points)) + 92.4
207.6 to 338.6	(0.00086 * ((points)^2)) - (0.82 * (points)) + 183.6
> 338.6	< 5%

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Description

Specialty

ICD-10