Ye et al reported a nomogram for evaluation of a patient for axial spondyloarthritis. The authors are from Wenzhou Medical University and affiliated hospitals in Xinjiang, China.
Patient selection: suspected axial spondyloarthritis
Parameters:
(1) age of the patient in years
(2) erythrocyte sedimentation rate (ESR) in mm in first hour, from 0 to 120
(3) Rad-Score, from -5 to 7, based on 15 features seen on MRI with equation in Supplementary Data S4
(4) gender (female 0, male 1)
(5) HLA-B27 status
points for age =
= 36.56 - (0.41 * (age))
points for ESR =
= 0.133 * (age)
points for Rad-Score =
= (8.33 * (score)) - 41.67
Parameter
|
Finding
|
Points
|
gender
|
female
|
0
|
|
male
|
2.5
|
HLA-B27
|
negative
|
0
|
|
positive
|
25.7
|
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 176.7
value of X =
= (0.098 * (score)) - 7.988
probability of axial spondyloarthropathy =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve was 0.90 for derivation and validation cohorts.