Nomogram of Xiong et al for Survival in a Woman with Metastatic Breast Cancer

Description

Xiong et al reported a nomogram for predicting survival of a woman with metastatic breast cancer. This can help to identify a woman who may benefit from more aggressive management. The authors are from Sun Yat-sen University, the State Key Laboratory of Oncology in Southern China and the Collaborative Innovation Center for Cancer Medicine in Guangzhou, China.

Patient selection: metastatic breast cancer, less than 70 years of age

Outcome: 3-year overall survival

Parameters:

(1) age in years

(2) metastasis-free interval

(3) metastatic sites

(4) hormone receptor status

Parameter	Finding	Points
age in years	< 35 years	56.5
	35 to 50 years	0
	> 50 years	47.3
metastasis-free interval	primary stage IV	36.3
	< 6 months	28.6
	6 months to 2 years	100
	2 to 5 years	69.2
	> 5 years	0
metastasis site	bone	0
	soft tissue	0
	visceral	71.4
	CNS	71.4
	multiple	100
hormone receptor status	positive	0
	negative	31.3

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 287.9

value of X =

= 1.25 - (0.000009201 * ((score)^2)) - (0.005665 * (score))

Score	3-Year Survival
< 65.4	> 70%
65.4 to 287.9	1 / (1 + EXP((-1) * X))

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Nomogram of Xiong et al for Survival in a Woman with Metastatic Breast Cancer

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