Nomogram of Varvarigou et al for Predicting Significant Hyperbilirubinemia in a Neonate Using Transcutaneous Bilirubin

Description

Varvarigou et al developed a nomogram for using transcutaneous bilirubin levels at various times after birth to predict the risk of significant hyperbilirubinemia in a term or near-term infant. This can help to identify a patient who may require more aggressive management. The authors are from University Hospital Patras in Greece.

Patient selection: gestational age >= 35 weeks and birth weight >= 2,000 g

Measurement: transcutaneous bilirubin in mg/dL using the Bilicheck bilirubinometer (SpectRx).

A neonate in the high risk group has a > 35% chance of significant hyperbilirubinemia, while it is < 0.5% in the low risk zone.

Postnatal Time in Hours	Points on the Lower Risk Line	Points on the Upper Risk Line
12	4.5 mg/dL	6.5 mg/dL
18	5.0 mg/dL	7.7 mg/dL
24	5.8 mg/dL	8.0 mg/dL
30	7.0 mg/dL	8.7 mg/dL
36	8.0 mg/dL	9.3 mg/dL
42	8.8 mg/dL	10.3 mg/dL
48	9.5 mg/dL	11.0 mg/dL
54	10.3 mg/dL	11.8 mg/dL
60	11.0 mg/dL	12.5 mg/dL
66	12.0 mg/dL	13.1 mg/dL
72	13.0 mg/dL	13.5 mg/dL

Lines for the Lower Risk Line

Postnatal Time in Hours	slope	intercept
12	0.076	3.646
18	0.143	2.434
24	0.187	1.384
30	0.175	1.737
36	0.131	3.313
42	0.114	4.020
48	0.125	3.535
54	0.128	3.354
60	0.168	0.929
66	0.167	1.040

Lines for the Upper Risk Line

Postnatal Time in Hours	slope	intercept
12	0.219	3.949
18	0.025	7.434
24	0.118	5.212
30	0.106	5.566
36	0.146	4.111
42	0.126	4.960
48	0.126	4.960
54	0.126	4.960
60	0.086	7.384
66	0.082	7.606

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Description

Specialty

ICD-10