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Description

Tang et al reported a nomogram for predicting survival of a patient with a neuroendocrine tumor of the thymus. The authors are from Qingdao University in China.


Patient selection: neuroendocrine tumor of the thymus

 

Parameters:

(1) chemotherapy

(2) surgery

(3) T status

(4) grade

 

Parameter

Finding

Points

chemotherapy

no

0

 

yes

5

surgery

yes

0

 

no

6.5

T status

Tx

0.6

 

T1

0

 

T2

4.8

 

T3

5.1

 

T4

10

grade/differentiation

well

0

 

intermediate/moderate

3

 

poor

2

 

unknown

9

 

where:

• Not sure how a tumor with unknown grade has a much greater risk than a poorly differentiated tumor.

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 30.5

 

value of X =

= (-0.0020465 * ((score)^2)) - (0.074498 * (score)) + 1.451

 

probability of 5-year survival =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curves i 0.71.


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