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Description

Pan et al reported a nomogram for predicting liver metastases in a patient with a neuroendocrine carcinoma. The authors are from Fujian Medical University in China.


Patient selection: pancreatic neuroendocrine carcinoma

 

Parameters:

(1) tumor grade

(2) tumor T stage

(3) tumor N stage

(4) diameter of tumor in cm

(5) metastatic site other than liver

 

Parameter

Finding

Points

tumor grade

G1

0

 

G2

19.6

 

G3

60

T stage

T1

0

 

T2

24.1

 

T3

31.1

 

T4

68.5

 

unspecified

100

N stage

N0

0

 

N1

31.5

 

unspecified

19.9

diameter

< 2 cm

0

 

2 to 4 cm

37.2

 

> 4 cm

74.2

 

unspecified

48.2

other sites with metastases

no

0

 

yes

57.4

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 323

 

value of X =

= (0.02371 * (score)) - 3.928

 

probability of liver metastases =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.85.


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