Pan et al reported a nomogram for predicting liver metastases in a patient with a neuroendocrine carcinoma. The authors are from Fujian Medical University in China.
Patient selection: pancreatic neuroendocrine carcinoma
Parameters:
(1) tumor grade
(2) tumor T stage
(3) tumor N stage
(4) diameter of tumor in cm
(5) metastatic site other than liver
Parameter |
Finding |
Points |
tumor grade |
G1 |
0 |
|
G2 |
19.6 |
|
G3 |
60 |
T stage |
T1 |
0 |
|
T2 |
24.1 |
|
T3 |
31.1 |
|
T4 |
68.5 |
|
unspecified |
100 |
N stage |
N0 |
0 |
|
N1 |
31.5 |
|
unspecified |
19.9 |
diameter |
< 2 cm |
0 |
|
2 to 4 cm |
37.2 |
|
> 4 cm |
74.2 |
|
unspecified |
48.2 |
other sites with metastases |
no |
0 |
|
yes |
57.4 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 323
value of X =
= (0.02371 * (score)) - 3.928
probability of liver metastases =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.85.
Specialty: Hematology Oncology