Nam et al developed a nomogram to help predict a man's risk of developing prostate cancer. This can help identify men who may benefit from closer monitoring. The authors are from Sunnybrook Health Sciences Centre, University of Toronto and the Cleveland Clinic.
Parameters:
(1) age of the patient in years
(2) race
(3) family history of prostate cancer
(4) AUA symptom score
(5) serum PSA in ng/mL
(6) ratio of free to total PSA
(7) digital rectal exam
|
Age in Years |
Points |
|
<= 35 |
0 |
|
35 - 95 |
(1.2817 * (age)) - 44.86 |
|
> 95 |
77 |
points for symptom score =
= (-0.337 * (symptom score)) + 13.2
|
Serum PSA |
Points |
|
0 to 4 |
(2.65 * (serum PSA)) |
|
4 to 50 |
(0.14348 * (serum PSA)) + 10.02 |
|
> 50 |
17.2 |
|
Ratio Free to Total PSA |
Points |
|
> 0.9 |
0 |
|
0.3 to 0.9 |
(-42.61 * (ratio)) + 38.34 |
|
0 to 0.3 |
(842.5 * ((ratio)^2)) - (502.7 * (ratio)) + 100.3 |
|
Parameter |
Finding |
Points |
|
race |
Asian |
1.8 |
|
|
Black |
16.6 |
|
|
White |
14 |
|
|
Other |
0 |
|
family history |
no |
0 |
|
|
yes |
9.5 |
|
digital rectal exam |
normal |
0 |
|
|
abnormal |
25.6 |
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 220+
• The higher the score the greater the risk for prostate cancer.
|
Total Score |
Risk of Developing Any Type of Prostate Cancer |
|
< 55 |
< 5% |
|
55 to 140.9 |
(0.004696 * ((score)^2)) - (0.3956 * (score)) + 12.61 |
|
140.9 to 212.5 |
(-0.004801 * ((score)^2)) + (2.288 * (score)) - 177.3 |
|
> 212.5 |
> 92% |
|
Total Score |
Risk of Developing High Grade Prostate Cancer |
|
< 55 |
< 2% |
|
55 to 165.8 |
(0.004108 * ((score)^2)) - (0.502 * (score)) + 17.59 |
|
165.8 to 212.5 |
(-0.004481 * ((score)^2)) + (2.436 * (score)) - 233.5 |
|
> 212.8 |
> 82% |
Specialty: Hematology Oncology, Surgery, general, Urology
