Patient selection: DLBCL with progression following frontline immunochemotherapy
Outcome: 24 month overall survival
Parameters:
(1) age in years at time of progression, from 40 to 80 years
(2) time to progression (TTP) in months after frontline immunochemotherapy, from 0 to 60 months
points for age =
= (-0.0005266 * ((age)^3)) + (0.10013 * ((age)^2)) - (4.8503 * (age)) + 67.65
points for time to progression over 15 to 60 months =
= 65.675 - (1.1144 * (months))
points for time to progression over 0 to 15 months =
= (-0.02975 * ((months)^2)) - (2.8976 * (months)) + 100.64
score =
= (points for age) + (points for TTP)
value of X =
= (-0.00012295 * ((score)^2)) - (0.015552 * (score)) + 1.7801
probability of 24 month overall survival =
= 1 / (1 + EP((-1) * X))
