Mari et al reported a nomogram for predicting significant renal function loss after a partial nephrectomy for a renal tumor. The authors are from multiple institutions in Italy.
Patient selection: renal tumor, being evaluated for robot-assisted partial nephrectomy.
Parameters:
(1) age in years, from 30 to 80
(2) sex
(3) Charlson comorbidity index (CCI), from 0 to 8
(4) diabetes mellitus
(5) baseline eGFR in mL per min per 1.73 sq m, from 15 to 135
(6) peripheral vascular disease
(7) surgical indication
(8) PADUA score, from 6 to 13
points for age =
= (0.062 * (age)) + 0.04
points for Charlson comorbidity index =
= 0.9875 * (CCI)
points for eGFR =
= 6.4125 - (0.0475 * (eGFR))
points for PADUA score =
= (0.7714 * (PADUA)) - 0.0286
|
Parameter
|
Finding
|
Points
|
|
sex of the patient
|
male
|
0
|
|
|
female
|
2.1
|
|
diabetes mellitus
|
no
|
0
|
|
|
yes
|
3
|
|
peripheral vascular disease
|
no
|
0
|
|
|
yes
|
1.5
|
|
surgical indication
|
elective
|
0
|
|
|
imperative
|
2.8
|
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 6.5
• maximum score: 38
value of X =
= (0.36 * (score)) - 6.569
probability of > 25% loss of eGFR at 4 years after surgery =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.82.
