Description

Manegold-Brauer et al reported a nomogram for predicting the total number of nucleated cells that can be collected by umbilical cord blood banking. This can help decide if sufficient hematopoietic stem cells are present. The authors are from University Hospital Basel and Women's Hospital, Kantospital Baselland in Switzerland.


 

Patient selection: singleton newborn with placenta for umbilical cord blood banking

 

Goal: prediction of total number of nucleated cells in a cord blood unit (CBU)

 

Parameters:

(1) parity of the mother

(2) gestational age in weeks

(3) gender of the infant

(4) fetal weight in grams

(5) maternal weight in kilograms on admission

(6) maternal height in cm

Parameter

Finding

Points

parity of the mother

1

24.4

 

> 1

0

gender

male

0

 

female

8.7

 

points for gestational age in weeks from 33 to 43 weeks =

= (4.85 * (weeks)) - 160.05

 

points for infant weight from 2,000 to 5,000 grams =

= (0.03333 * (weight)) - 66.666

 

points for maternal weight from 50 to 150 kilograms =

= (0.37 * (weight)) - 18.5

 

points for maternal height from 140 to 190 cm =

= (-0.748 * (height)) + 142.12

 

total score =

= SUM(points for all 6 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 256

• The higher the score the greater the likelihood that the TNC count will be > 150 * 10^7.

 

Score

Probability of TNC Count > 150 * 10^7

< 109

< 10%

109 to 201

(0.00297 * ((score))^2) - (0.2497 * (score)) + 1.11

> 201

> 70%

 


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