Nomogram of Ma et al for Diffuse Large B-Cell Lymphoma (DLBCL)

Description

Ma et al reported a nomogram for evaluating a patient with diffuse large B-cell lymphoma (DLBCL). The authors are from Sun Yat-sen University, State Key Laboratory of Oncology in South China and Imperial College London.

Patient selection: diffuse large B-cell lymphoma

Parameters:

(1) age in years

(2) type of lymphoma based on the cell of origin (COO)

(3) therapy with rituximab

(4) ECOG performance status

(5) serum LDH in U/L, versus upper limit of normal (ULN)

(6) risk based on immune risk score

Parameter	Finding	Points
age in years	LTE 60 years	0
	GT 60 years	65
cell of origin	germinal center B cell	0
	non-GCB	50.5
rituximab therapy	no	31.8
	yes	0
ECOG PS	< 2	0
	>= 2	61.2
serum LDH	<= ULN	0
	> ULN	43
immune risk score	low risk	0
	high risk	100

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 351.5

value of X =

= (-0.00003618 * ((score)^2)) - (0.007124 * (score)) + 2.237

probability of 5-year survival =

= 1 / (1 + EXP((-1) * X))

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