Lu et al reported a nomogram for evaluating a patient with Burkitt lymphoma. This can help to identify a patient who may require more aggressive management. The authors are from Guangzhou Medical University in China.
Patient selection> Burkitt lymphoma
Outcome: 5-year overall survival
Parameters:
(1) age in years
(2) race
(3) chemotherapy
(4) primary site
(5) stage
Parameter |
Finding |
Points |
age in years |
<= 20 years |
0 |
|
21 to 40 years |
32.6 |
|
41 to 59 years |
65.2 |
|
>= 60 years |
97.8 |
race |
Black |
0 |
|
White |
2.1 |
|
American Indian or Alaskan Native |
4.3 |
|
Chinese |
6.2 |
|
Other Asian or Pacific Islander |
7.8 |
chemotherapy |
yes |
0 |
|
no |
100 |
primary |
lymph node |
0 |
|
GI tract |
2.3 |
|
oral cavity or pharynx |
4.6 |
|
other |
6.9 |
|
bone marrow or nervous system |
9.2 |
stage |
I |
0 |
|
II |
18.9 |
|
III |
37.9 |
|
IV |
56.7 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 271.5
• The higher the score the worse the overall survival.
Total Score |
Value of X |
0 to 113 |
2.761 - (0.02058 * (score)) |
113 to 271.5 |
(-0.00015472 * ((score)^2)) + (0.016569 * (score)) + 0.48907 |
probability of 5-year overall survival =
= 1 / (1 + EXP((-1) * X))
Specialty: Hematology Oncology