Lin et al reported a nomogram for predicting acute respiratory distress syndrome (ARDS) occurring in a patient with adenoviral pneumonia. This can help to identify a patient who may benefit from more aggressive management. The authors are from Central South University, Xiangya Hospital, Zhushou Central Hospital and affiliated laboratories in Changsha, China.
Patient selection: adenoviral pneumonia, immunocompetent, adult from 25 to 55 years
Parameters:
(1) dyspnea
(2) SOFA score from 0 to 20
(3) serum LDH in IU/L from 0 to 3,500
(4) ventilatory support
points for SOFA =
= 5 * (SOFA score)
points for serum LDH =
= 0.0239 * (LDH)
Parameter
Finding
Points
dyspnea
no
0
yes
22.8
ventilatory support
non-invasive ventilation
25.6
mechanical ventilation
25.6
none
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 231.8
value of X =
= (0.0625 * (score)) - 3.932
probability of ARDS =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.90.
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