Description

Liang et al reported a nomogram for predicting overall survival for a patient with Hodgkin's disease. The authors are from Hangzhou Medical College, Guangdong Medical University, Southern Medial University, Sun-Yat-sen University, Shenzhen University, and affiliated hospitals.

 


Patient selection: Hodgkin's disease

 

Parameters:

(1) Hodgkin disease subtype

(2) clinical stage

(3) radiation therapy

(4) chemotherapy

 

Parameter

Finding

Points

subtype

nodular lymphocyte predominant

0

 

nodular sclerosis

33

 

lymphocyte rich

40

 

mixed cellularity

62.5

 

lymphocyte depleted

100

 

NOS

70

clinical stage

I

0

 

II

4

 

III

41

 

IV

60

radiation therapy

no

41.2

 

yes

0

chemotherapy

no

70.3

 

yes

0

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 271.5

 

value of X =

= (-0.00008503 * ((score)^2)) + (0.0006126 * (score)) + 2.967

 

predicted 5-year survival =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve for 5-year survival was 0.71.


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