Description

Li et al reported a nomogram for predicting new osteoporotic vertebral fractures after vertebral augmentation of osteoporotic vertebral compression fractures.

The authors are from People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, and Sichuan University in China.


Patient selection: status post vertebral augmentation of osteoporotic vertebral compression fractures

 

Parameters:

(1) age in years

(2) dosage of bone cement in mL

(3) anti-osteoporosis treatment

(4) bone cement dispersion

(5) contact with vertebral body endplate

 

Parameter

Finding

Points

age in years

< 60 years

0

 

60 to 70 years

50

 

70 to 80 years

61.9

 

> 80 years

98

dose of bone cement

< 3 mL

38.6

 

3 to 4 mL

44.6

 

4 to 4.5 mL

0

 

> 4.5 mL

92.4

anti-osteoporosis therapy

no

100

 

yes

0

bone cement dispersion

good

0

 

bad

33.4

contact with endplate

no

96.5

 

yes

0

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 473.7

 

value of X =

= (0.02277 * (score)) - 7.468

 

probability of refracture =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.88 in the derivation and 0.87 in the validation cohorts.


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