Lang et al developed a nomogram for predicting the 10-year disease recurrence rate for a patient with papillary thyroid carcinoma. The authors are from the University of Hong Kong and Seoul National University.
Patient selection: papillary thyroid carcinoma
Outcome: 10-year disease recurrence rate
Parameters:
(1) age in years
(2) gender
(3) size of the tumor in cm
(4) extension beyond the thyroid
(5) lymph node metastasis (N status)
(6) lymphovacular invasion
|
Parameter |
Finding |
Points |
|
age in years |
< 30 years |
7 |
|
|
30 to 50 years |
0 |
|
|
> 50 years |
3 |
|
Gender |
female |
0 |
|
|
male |
4 |
|
size in cm |
< 2 cm |
0 |
|
|
2 to 4 cm |
5 |
|
|
> 4 cm |
7 |
|
extrathyroid extension |
no |
0 |
|
|
yes |
4 |
|
N status |
N0 or Nx |
0 |
|
|
N1a |
9 |
|
|
N1b |
12 |
|
lymphovascular invasion |
no |
0 |
|
|
yes |
4 |
total score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 38
• The higher the score the greater the 10-year disease recurrence rate.
|
Score |
10-year disease-specific mortality |
|
0 to 32 |
(0.0593 * ((points)^2)) + (0.0791 * (points)) + 2.899 |
|
> 32 |
> 65% |
Specialty: Hematology Oncology, Surgery, general, Endocrinology
