Jeldres et al developed a nomogram for predicting survival for a patient with an upper urinary tract urothelial carcinoma. This can help to identify a patient who may benefit from more aggressive or novel therapy. The authors are from the University of Montreal, Vita-Salute San Raffaele (Milan), Martini Clinic (Hamburg), and Weill Cornell Medical Center (New York City).
Parameters:
(1) age in years
(2) pathologic T stage
(3) pathologic N stage
(4) histologic grade
points for age =
= MIN(100, (1.25 * (age in years)) - 25)
Parameter |
Finding |
Points |
pathologic T stage |
T1 |
0 |
|
T2 |
21.9 |
|
T3 |
54.7 |
|
T4 |
67.1 |
pathologic N stage |
pN0 (none) |
0 |
|
pN1 or higher (any) |
5.3 |
|
pNx (unknown) |
50 |
histologic grade |
G1 (well-differentiated) |
0 |
|
G2 |
16 |
|
G3 |
32 |
|
G4 |
48 |
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 264
• The higher the score the worse the prognosis.
Points |
Probability of 5-Year Cancer Specific Mortality |
< 18.6 |
> 98% |
18.6 to 132 |
(-0.001418 * ((points)^2)) + (0.0579 * (points)) + 97.23 |
132 to 238 |
(-0.001302 * ((points)^2)) - (0.2032 * (points)) + 130.6 |
> 238 |
< 10% |
Specialty: Hematology Oncology, Surgery, general, Urology