Huo et al reported a nomogram for predicting cachexia in a cancer patient. The authors are from Army Medical University, Jilin University, Capital Medical University and Key Laboratory of Cancer Beijing.
Patient selection: cancer
Parameters:
(1) age of the patient, from 0 to 120 years
(2) Nutritional Risk Screen 2002 (NRS2002), from 0 to 6
(3) patient generated subjective global assessment (PG-SGA), from 0 to 26
(4) EORTC QLQ-C quality of life, from 30 to 100
(5) cancer category, from 0 to 9 (lung, colorectal, gastric, breast, leukemia, liver, esophagus, pancreas, cervix, other)
points for age =
= 42 - (0.35 * (age))
points for NRS2002 =
= 6.367 * (NRS2002)
points for PGSGA =
= 3.846 * (PG-SGA)
quality of life score =
= 33.2857 - (0.3329 * (QOL))
points for cancer category =
= 0.4333 * (category)
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 207.4
value of X =
= (0.1106 * (score)) - 9.388
probability of cancer cachexia =
= 1 / (1 + EXP((-10 * X))
Performance:
• The area under the ROC curve was 0.92.
