Patient selection: resection of a hepatocellular carcinoma
Outcome: liver failure after surgery
Parameters:
(1) platelet count in 10^9/L
(2) ElastPQ (Elast point quantitative) values in kPa from shear wave elastography (on the Philips Ultrasound Elasto system)
(3) serum total bilirubin in µmol/L
(4) clinical signs of portal hypertension
(5) serum GGT in U/L
points for platelet count =
= (-0.1538 * (platelet coefficient in 10^9/)) + 100
points for ElastPQ =
= (2.975 * (ElastPQ)) - 5.95
points for serum total bilirubin =
= (1.70667 * (bilirubin)) - 8.5333
points for portal hypertension =
= (9.5 if present, else 0)
points for serum GGT =
= (0.05166 * (GGT))
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 302.2
|
Total Score
|
Hepatic Failure in percent
|
|
< 60
|
< 1%
|
|
60 to 208
|
X = (0.06217 * (score)) - 8.323;
probability = 1 / (1+EXP((-1)*X))
|
|
> 208
|
> 99%
|
Performance:
• The area under the ROC curve is 0.82.
