Eom et al developed a nomogram for predicting survival of gastric cancer patients after curative surgery in Korea. It has subsequently been validated in other populations. The authors are from multiple hospitals in the Republic of Korea.
Patient selection: gastric cancer patient after curative resection
Outcome: 5-year survival
Parameters:
(1) age in years
(2) lymph node dissection
(3) location in the stomach
(4) lymphovascular invasion
(5) size in cm
(6) depth of invasion
(7) number of lymph nodes with metastase
Parameter |
Finding |
Points |
age in years |
< 40 |
29 |
|
40 to 50 |
35.5 |
|
50 to 60 |
0 |
|
60 to 70 |
44.7 |
|
> 70 |
65 |
lymph node dissection |
D1 |
25 |
|
D2 |
0 |
location in the stomach |
upper |
0 |
|
middle |
7.2 |
|
lower |
23 |
|
whole |
56.6 |
lymphovascular invasion |
no |
0 |
|
yes |
34 |
size in cm |
< 5 cm |
0 |
|
5 to 10 cm |
11.2 |
|
> 10 cm |
33.6 |
depth of invasion |
mucosa or submucosa |
0 |
|
muscularis propria |
43.3 |
|
subserosa |
84.5 |
|
serosa |
100 |
number of LN with metastases |
0 |
0 |
|
1 or 2 |
27.6 |
|
3 to 6 |
51 |
|
>= 7 |
91 |
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 395.2
• The higher the score the worse the 5-year survival.
Total Score |
5-Year Survival |
< 118 |
> 90% |
118 to 347.4 |
(-0.0008603 * ((score)^2)) + (0.03341 * (score)) + 99.2 |
> 347.4 |
< 10% |
Performance:
• The area under the ROC curve was 0.83.
Specialty: Hematology Oncology, Gastroenterology