Deng et al reported a nomogram for predicting the risk of acute kidney injury (AKI) in a septic patient admitted to the intensive care unit (ICU). This can help to identify a patient who may benefit from more aggressive management. The authors are from Xiangya Hospital and Central South University in Hunan, China.
Patient selection: septic patient admitted to the ICU
Outcome: acute kidney injury in the first 24 hours (S-AKI)
Parameters:
(1) infusion volume in mL, from 0 to 22,000 mL
(2) serum BUN in mg/dL, from 0 to 130
(3) blood lactate in mmol/L, from 0 to 16
(4) body weight in kilograms from 0 to 200
(5) temperature in °C, from 31 to 41
(6) serum chloride in mmol/L, from 80 to 135
(7) age in years, from 10 to 100
points for infusion volume =
= (0.0009545 * (volume))
points for serum BUN =
= (0.76923 * (BUN))
points for blood lactate =
= (1.6875 * (lactate))
points for body weight =
= (0.1375 * (weight))
points for temperature =
= 75.85 - (1.85 * (temperature))
points for serum chloride=
= (0.36255 * (chloride)) - 29.0036
points for age =
= (0.084889 * (age)) - 0.84889
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 221.69
• The higher the score the greater the risk of acute kidney injury.
value of X =
= (0.09967 * (score)) - 5.639
probability of AKI =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.80.
