Cheng et al reported a nomogram for predicting refractory Mycoplasma pneumonia in a child. This can help to identify a patient who may require more aggressive management. The authors are from Central South University in Changsha, National Clinical Research Center for Child Health and Disorders, Children's Hospital of Chongqing and Chongqing Medical University in China.
Patient selection: child with Mycoplasma pneumoniae pneumonia
Parameters:
(1) high fever
(2) serum albumin, from 10 to 55 g/L
(3) serum LDH, from 0 to 1430 IU/L
(4) neutrophil ratio, from 0.239 to 0.9 (presumably percent neutrophils in differential count)
High Fever
|
Points
|
No
|
44.8
|
Yes
|
68.55
|
points for albumin =
= 118.6 - (1.858 * (albumin))
line for LDH =
= (0.05425 * (LDH)) + 22.41
points for neutrophil ratio =
= (96.92 * (ratio)) - 23.21
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 402
X =
= (0.0733 * (score)) - 15.43
probability of refractory disease =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.88.