Chen et al reported a nomogram for predicting recurrence-free survival for a patient with a gastrointestinal stromal tumor (GIST). This can help to identify a patient who may benefit from more aggressive management. The authors are from Southern Medical University and Sun Yat-sen University in China.
Patient selection: GI stromal tumor
Parameters:
(1) diameter of the tumor in cm
(2) site
(3) percent staining with Ki-67
(4) mitotic count per 50 high power fields
Parameter
Finding
Points
diameter
> 5 cm
0
<= 5 cm
100
site
gastric
74.7
non-gastric
0
Ki-67 staining
<= 6%
77.0
> 6%
0
mitotic count
<= 5 per 50 hpf
53.1
> 5 per 50 hpf
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 304.8
• The higher the score the greater the 5-year recurrence-free survival.
value of X =
= (0.01843 * (score)) - 1.706
probability of 5-year recurrence free survival =
= 1 / (1 + EXP((-1) * X))
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