Nomogram of Berardi et al for Predicting Complications Following Resection of Hepatocellular Carcinoma in a Patient with the Metabolic Syndrome

Description

Berardi et al reported a nomogram for predicting major complications following resection of a hepatocellular carcinoma occurring in a patient with the metabolic syndrome. The authors are from multiple institutions in the United States, Canada, and Europe.

Patient selection: hepatic resection of a hepatocellular carcinoma with the metabolic syndrome

Outcome: major morbidity or death

Parameters:

(1) body mass index (BMI) in kg per sq meter

(2) diabetes

(3) ischemic heart disease

(4) portal hypertension

(5) approach for hepatectomy

(6) type of hepatectomy

(7) EASL classification

Parameter	Finding	Points
body mass index	< 30 kg per sq m	0
	>= 30 kg per sq m	16.79
diabetes	no	0
	yes	22.17
ischemic heart disease	no	0
	yes	31.51
portal hypertension	no	0
	yes	64.53
surgical approach	minimally invasive	0
	open	38
type of hepatectomy	minor	0
	major	100
EASL classification	normal parenchyma	21.38
	non-alcoholic fatty liver	0
	NASH	59.39
	cirrhosis	85.36

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 358.36

value of X =

= (0.0151 * (score)) - 4.177

risk of major complications =

= 1 / (1 + EXP((-1) * X))

Performance:

• The area under the ROC curve was 0.73.

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Nomogram of Berardi et al for Predicting Complications Following Resection of Hepatocellular Carcinoma in a Patient with the Metabolic Syndrome

Description

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