Ardoino et al developed a nomogram for predicting survival of a patient with a retroperitoneal soft tissue sarcoma. The authors are from Instituto Nazionale Tumori and the University of Milan in Italy.
Patient selection: age 18 to 80
Parameters:
(1) age
(2) type of soft tissue sarcoma
(3) histologic grade
(4) diameter in cm
(5) surgical margins of excision
points for age =
= (0.8405 * (age in years)) - 15.21
|
Diameter in cm |
Points |
|
0 to 25 cm |
MAX(0,(-0.096 * ((diameter)^2)) + (5.33 * (diameter)) - 1.479) |
|
25 to 70 cm |
(-0.000336 * ((diameter)^2)) - (0.07283 * (diameter)) + 91.99 |
|
> 70 cm |
48 |
|
Parameter |
Finding |
Points |
|
grade |
grade I |
0 |
|
|
grade II |
53.6 |
|
|
grade III |
91.25 |
|
type of sarcoma |
solitary fibrous tumor (SFT) |
0 |
|
|
leiomyosarcoma |
59.2 |
|
|
malignant peripheral nerve sheath tumor |
70 |
|
|
liposarcoma |
80 |
|
|
other |
100 |
|
margins |
microscopic positive |
0 |
|
|
macroscopic positive |
64 |
total points =
= SUM(points for all 5 parameters)
Interpretation:
• minimum points:
• maximum points: 378
• The higher the score the worse the patient's survival.
|
Points |
10 Year Survival |
|
< 80 |
> 95% |
|
80 to 190 |
(-0.003012 * ((points)^2)) + (0.4534 * (points)) + 77.71 |
|
190 to 262 |
(0.00313 * ((points)^2)) - (2.134 * (points)) + 348.4 |
|
> 262 |
< 5% |
Specialty: Hematology Oncology, Surgery, general, Surgery, orthopedic
