Description

The International Nonproprietary Names (INN) Programme of the World Health Organization (WHO) has developed a nomenclature to standardize the names of monoclonal antibodies.


 

Elements of the name:

(1) prefix - specific to the particular product

(2) substem A - indicates the target

(3) substem B - indicates species that is the source for the immunoglobulin

(3) suffix - indicates type of monoclonal antibody (mab or nab)

Substem A

Target Class

b or ba

bacterial

c or ci

cardiovascular

f or fu

fungal

l or li

immunomodulatory

s or so

bone

t or tu

tumor

tox or toxa

toxin

v or vi

viral

 

 

Substem B

Type of Monoclonal Antibody

a

rat

e

hamster

i

primate

o

murine

u

fully human

xi

chimeric

xizu

chimeric and humanized

zu

humanized

 


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