Adhoute et al reported the NIACE score which was named for the five components. This can separate patients into two groups with different overall survival. The authors are from multiple hospitals in France.
Patient selection: advanced hepatocellular carcinoma (BCLC stage C), Child-Pugh stage A or B
Parameters:
(1) nodules (N)
(2) infiltrative tumor (I)
(3) serum AFP in ng/mL (A)
(4) Child-Pugh stage (C)
(5) ECOG (E)
Parameters
Findings
Points
nodules
1 or 2
0
>= 3
1
infiltrative tumor
no
0
yes
1.5
serum AFP
< 200 ng/mL
0
>= 200 ng/mL
1.5
Child-Pugh stage
A
0
B
1.5
ECOG
0
0
>= 1
1.5
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 7
• A score <= 3 was associated with a better overall survival than a score > 3.
To read more or access our algorithms and calculators, please log in or register.
