Central nervous system:
(1) extrapyramidal findings (Parkinsonian tremor, choreoathetosis)
(2) cerebellar degeneration
(3) posterior column dysfunction
(4) cognitive and memory impairment
(5) psychiatric or mood disorders (excessive emotional outbursts, apathy, psychosis, etc)
(6) encephalopathy
Peripheral nervous system:
(1) polyneuropathy, motor and/or sensory
(2) autonomic dysfunction
Ophthalmologic:
(1) optic neuritis/neuropathy with visual impairment
(2) central scotomata
(3) impaired color discrimination
(4) ptosis
(5) disorders of ocular motility
With Prussian Blue therapy many of the neurological deficits may improve over time.
