Neurological Manifestations of African Trypanosomiasis

Types of disturbances include:

(1) psychiatric

(2) sleep

(3) motor

(4) sensory

(5) reflexes

(6) terminal

 

Psychiatric disturbances:

(1) anxiety

(2) irritability

(3) lassitude

(4) mania or agitation

(5) violent and suicidal behavior

(6) uncontrollable sexual impulses

(7) delirium

(8) hallucinations

 

Sleep disturbances:

(1) daytime somnolence

(2) nocturnal insomnia

(3) narcoleptic crisis (deep sleep from which it is impossible to wake, followed by amnesia)

(4) uncontrollable urges to sleep in the final stage

 

Motor disturbances:

(1) tremors of tongue and limbs

(2) muscle fasciculations

(3) slurred speech

(4) cerebellar ataxia

(5) abnormal movements

(6) focal motor weakness

(7) extensor plantar response

(8) neuritis or polyneuritis

 

Sensory disturbances:

(1) pruritis

(2) paresthesias

(3) hyperesthesias

(4) anesthesia

 

Abnormal reflexes:

(1) palmo-mental

(2) pout

 

Terminal manifestations:

(1) seizures

(2) cerebral edema

(3) progressive mental deterioration

(4) incontinence