Neurosarcoidosis is an uncommon condition that may be unfamiliar to many clinicians. It may present with a number of syndromes, some specific and others nonspecific for the condition. The authors are from Southmead Hospital and the University of Bristol in the UK.
Neurologic syndromes associated with neurosarcoidosis - nonspecific:
(1) aseptic meningitis
(2) cranial neuropathy
(3) peripheral polyneuropathy
(4) raised intracranial pressure
(5) seizures
(6) stroke, ischemic or hemorrhagic
(7) dural venous sinus thrombosis
(8) optic neuritis
(9) Guillain-Barre syndrome
(10) focal myelitis
(11) radiculitis
(12) diffuse encephalopathy
(13) focal or multifocal lesions
(14) psychiatric (behavioral change, psychosis, confusion)
(15) hydrocephalus
Neurologic syndromes associated with neurosarcoidosis - more specific:
(1) uveoparotid fever
(2) hypothalamic and pituitary dysfunction (diabetes insipidus, galactorrhea, etc)
(3) longitudinally extensive myelitis
(4) conus or cauda equina syndrome
