Description

Neonatal outcome in extremely low birthweight infants can be predicted using data available before delivery using equations developed by Bahado-Singh et al. The study was done at the Yale University in New Haven, Connecticut.


 

Infant selection: birthweight <= 1,000 grams

 

Parameters:

(1) gestational age in weeks

(2) abdominal circumference in millimeters

 

probability of overall survival =

= EXP(-X) / (1 + EXP(-X))

 

X =

= 20.8384 - (0.5553 * (gestational age in weeks)) - (0.03999 * (abdominal circumference in mm))

 

probability of survival without severe morbidities =

= EXP(-Y) / (1 + EXP(-Y))

 

Y =

= 29.8361 - (0.7518 * (gestational age in weeks)) - (0.0415 * (abdominal circumference in mm))

 

where:

• survival indicates being alive at hospital discharge

• severe neonatal morbidities include high grade retinopathy of prematurity, high grade intraventricular hemorrhage, periventricular leukomalacia, chronic lung disease and deafness

• outcomes could be predicted independent of birthweight

 

NOTE: The equations given above are given on page 465 as:

 

probability of overall survival =

= 1 / (1 + (EXP((-1) * (20.8384 + (0.5553 * (gestational age)) + (0.03999 * (abdominal circumference in mm))))))

 

probability of survival without severe morbidities =

= 1 / (1 + (EXP((-1) * (29.8361 + (0.7518 * (gestational age)) + (0.0415 * (abdominal circumference in mm))))))

 

When these equations are used, the results do not resemble the data shown in Figures 3 and 4 on page 466.


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