Description

Janota et al reported the Neonatal Multiple Organ Dysfunction (NEOMOD) score for evaluating premature infants in the neonatal intensive care unit. This can help to identify a neonate who is at high risk for mortality. The authors are from the Institute for the Care of Mother and Child in Prague.


 

Patient selection: premature infant in the neonatal intensive care unit (NICU)

 

Parameters:

(1) central nervous system changes on imaging studies

(2) hemocoagulation balance (platelet count)

(3) respiratory system

(4) gastrointestinal system

(5) cardiovascular system

(6) renal system (urine output)

(7) acid-base balance (base deficit)

Parameter

Findings

Points

CNS system

no hemorrhage OR hemorrhage limited to subependymal germinal matrix

0

 

intraventricular hemorrhage

1

 

intraparenchymal blood, hydrocephalus, leukomalacia, cerebral atrophy

2

platelet count (hemocoagulation)

> 100,000 per µL

0

 

30,000 to 100,000 per µL

1

 

< 30,000 per µL

2

respiratory system

spontaneous respirations

0

 

need for continuous positive airway pressure OR FIO2 > 21%

1

 

mechanical ventilation

2

gastrointestinal system

enteral feeding

0

 

total parenteral nutrition (TPN)

1

 

necrotizing enterocolitis

2

cardiovascular system

adequate blood pressure

0

 

continuous pressor support to maintain adequate blood pressure

1

 

hypotension despite pharmacological support

2

urine output (renal system)

> 1 mL/kg per hour

0

 

0.2 to 1.0 mL/kg per hour

1

 

< 0.2 mL/kg per hour

2

base deficit (acid-base balance)

< 7 mEq/L

0

 

7 to 15 mEq/L

1

 

> 15 mEq/L

2

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 14

• A score >=9 was associated with 100% mortality (corresponds to 4+ organ failures).

 


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