Negative intrathoracic pressure can result in negative pressure pulmonary edema (NPPE). This can be a life-threatening condition. It may be associated with flash pulmonary edema (see previous section).
Conditions associated with NPPE:
(1) laryngospasm following general anesthesia
(2) acute epiglottitis
(3) strangulation
(4) tracheal compression by a large thyroid goiter
(5) any other cause of upper airway obstruction
Prompt recognition and treatment usually results in rapid resolution.
Complications include:
(1) diffuse intra-alveolar hemorrhage
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