Description

Faraklas et al reported the Necrotizing Soft Tissue Infection (NSTI) risk calculator. This can help to identify a patient who may benefit from more aggressive management. The authors are from the University of Utah in Salt Lake City.


 

Patient selection: necrotizing soft tissue infection undergoing surgical debridement

 

Parameters:

(1) age in years

(2) disability (dependency)

(3) dialysis status

(4) ASA class

(5) emergency surgery

(6) preoperative septic shock

(7) platelet count

 

Parameter

Finding

Odds Ratio

Coefficient

age in years

<= 60 years of age

1

0

 

> 60 years of age

2.47

0.904

disability

none

1

0

 

partial

1.61

0.476

 

complete

2.33

0.846

dialysis before surgery

no

1

0

 

yes

1.89

0.637

ASA class

1, 2 or 3

1

0

 

4 or 5

3.55

1.267

emergency surgery

no

1

0

 

yes

1.555

0.4416

preoperative septic shock

no

1

0

 

yes

2.3534

0.8558

platelet count

>= 150,000 per µL

1

0

 

50,001 to 149,999

1.67

0.513

 

<= 50,000 per µL

3.48

1.247

 

where:

• The coefficient is related to the odds ratio: odds ratio = EXP(coefficient)

 

X =

= SUM(coefficients for all 7 parameters) – 4.4293

 

probability of survival =

= 1 / (1 + EXP((-1) *X))

 

probability of mortality =

= 1 – (probability of survival)

 


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