Faraklas et al reported the Necrotizing Soft Tissue Infection (NSTI) risk calculator. This can help to identify a patient who may benefit from more aggressive management. The authors are from the University of Utah in Salt Lake City.
Patient selection: necrotizing soft tissue infection undergoing surgical debridement
Parameters:
(1) age in years
(2) disability (dependency)
(3) dialysis status
(4) ASA class
(5) emergency surgery
(6) preoperative septic shock
(7) platelet count
Parameter |
Finding |
Odds Ratio |
Coefficient |
age in years |
<= 60 years of age |
1 |
0 |
|
> 60 years of age |
2.47 |
0.904 |
disability |
none |
1 |
0 |
|
partial |
1.61 |
0.476 |
|
complete |
2.33 |
0.846 |
dialysis before surgery |
no |
1 |
0 |
|
yes |
1.89 |
0.637 |
ASA class |
1, 2 or 3 |
1 |
0 |
|
4 or 5 |
3.55 |
1.267 |
emergency surgery |
no |
1 |
0 |
|
yes |
1.555 |
0.4416 |
preoperative septic shock |
no |
1 |
0 |
|
yes |
2.3534 |
0.8558 |
platelet count |
>= 150,000 per µL |
1 |
0 |
|
50,001 to 149,999 |
1.67 |
0.513 |
|
<= 50,000 per µL |
3.48 |
1.247 |
where:
• The coefficient is related to the odds ratio: odds ratio = EXP(coefficient)
X =
= SUM(coefficients for all 7 parameters) – 4.4293
probability of survival =
= 1 / (1 + EXP((-1) *X))
probability of mortality =
= 1 – (probability of survival)
Specialty: Infectious Diseases, Surgery, general
ICD-10: ,