Filipovich et al developed criteria for the severity of chronic graft-versus-host disease (GVHD) for the National Institutes of Health. After various sites are score they can be combined into a global score.
Patient selection: chronic GVHD
Parameters:
(1) grade for pulmonary involvement
(2) number of non-pulmonary organs or sites with Grade 1, excluding performance status
(3) number of non-pulmonary organs or sites with Grade 2, excluding performance status
(4) number of non-pulmonary organs or sites with Grade 3, excluding performance status
Lung Grade |
Grade 1 |
Grade 2 |
Grade 3 |
Severity |
0 |
1 or 2 |
0 |
0 |
mild |
NA |
NA |
>=1 |
0 |
moderate |
1 |
NA |
NA |
0 |
moderate |
NA |
>= 3 |
NA |
0 |
moderate |
NA |
NA |
NA |
>= 1 |
severe |
>= 2 |
NA |
NA |
NA |
severe |
Specialty: Immunology/Rheumatology