Marchal-Bressenot et al reported a histologic index for ulcerative colitis (UC). The authors are from multiple institutions in Europe including the Universite de Lorraine, Vandoeuvre-les-Nancy, France.
Patient selection: ulcerative colitis
Parameters:
(1) chronic inflammatory infiltrate
(2) acute inflammatory cell infiltrate
(3) ulceration
|
Parameter |
Finding |
Points |
|
chronic inflammatory infiltrate |
none |
0 |
|
|
mild |
1 |
|
|
moderate or severe |
3 |
|
ulceration |
no |
0 |
|
|
yes |
2 |
|
acute inflammatory infiltrate |
none |
0 |
|
|
mild |
2 |
|
|
moderate |
3 |
|
|
severe |
4 |
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 9
|
Ulceration |
Acute Inflammation |
Chronic Inflammation |
Grade |
|
yes |
NA |
NA |
4 |
|
no |
moderate or severe |
NA |
3 |
|
no |
mild |
NA |
2 |
|
no |
no |
moderate or marked |
1 |
|
no |
no |
no or mild |
0 |
|
Grade |
Term |
|
0 |
severely active disease |
|
1 |
moderately active disease |
|
2 |
mildly active disease |
|
3 |
chronic inflammatory with no acute inflammatory infiltrate |
|
4 |
no histological significant disease |
Specialty: Gastroenterology
