Nakalanga Syndrome was first described in Uganda in 1962 and is associated with Onchocerca volvulus.
Patient selection: lives in a region where Onchocerca volvulus is endemic or hyperendemic
Clinical features:
(1) dwarfism that appears in children who had been developing normally prior to onset
(2) delayed sexual development
(3) mental retardation
(4) facial stigmata (small mandible, protruding teeth)
(5) kyphoscoliosis
(6) variable generalized seizures
Control of onchocerciasis is associated with disappearance of the syndrome.
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Specialty: Infectious Diseases
