Description

Chang et al reported the MYSTIC score for evaluating a patient with significant traumatic brain injury (TBI). This can help to predict mortality without early withdrawal of life-sustaining treatments. The authors are from the University of Massachusetts.


Patient selection: moderate to severe traumatic brain injury (TBI)

 

Parameters:

(1) age in years

(2) pupils

(3) Marshall CT score

(4) motor score for Glasgow coma scale (GCS)

(5) hypotension

(6) hypoxia

(7) subarachnoid hemorrhage on first head CT

(8) epidural hematoma on first head CT

(9) sepsis

(10) SIRS

(11) urinary tract infection

(12) acute renal failure

(13) cardiac arrest

(14) brain edema

(15) cerebellar herniation

 

Parameter

Finding

Points

age

< 60 years

0

 

60 to 79 years

1

 

>= 80 years

21

pupil reactivity

both

0

 

one

1

 

none

14

Marshall CT score

2

0

 

3

1

 

4 to 6

3

motor score GCS

6

0

 

4 or 5

1

 

2 or 3

17

 

1

4

hypotension

no

0

 

yes

4

hypoxia

no

0

 

yes

10

subarachnoid hemorrhage

no

0

 

yes

1

epidural hematoma

no

13

 

yes

0

sepsis

no

12

 

yes

0

SIRS

no

0

 

yes

10

UTI

no

14

 

yes

0

acute renal failure

no

0

 

yes

17

cardiac arrest

no

0

 

yes

22

brain edema

no

0

 

yes

9

cerebellar herniation

no

0

 

yes

13

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score:180

• The higher the score the greater the risk of death.

 

Total Score

Mortality

0 to 42

1-2%

43 to 53

8-9%

54 to 64

21%

65 to 81

60%

>= 82

90%

 

Performance:

• The area under the ROC curve was 0.94.


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