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Myeloma Staging System of Durie and Salmon

Specialty:

Hematology Oncology

Objective:

ICD-10:

Description:

Multiple myeloma involves a malignant proliferation of plasma cells. As the disease progresses, tumor replaces the marrow causing anemia, forms osteolytic bone lesions causing hypercalcemia and fractures, and produces increasing amounts of the associated monoclonal protein(s). The method of Durie and Salmon is estimates tumor burden based on myeloma protein synthesis rates and a calculation of the total body tumor cell mass.

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