Muscarinic Effects of a Cholinergic Agent

Muscarinic effects:

(1) blurring of vision (effect on the ciliary body)

(2) miosis

(3) urinary frequency with incontinence

(4) bradycardia

(5) hypotension

(6) atrial fibrillation and/or ventricular tachycardia

(7) increased lacrimation

(8) rhinitis

(9) increased salivation

(10) increase sweating

(11) nausea and vomiting

(12) abdominal cramping

(13) diarrhea or fecal incontinence with tenesmus

(14) chest tightness

(15) wheezing and bronchospasm

(16) cough

(17) increased bronchial secretions

(18) dyspnea with or without cyanosis

The mnemonic SLUDGEM may be used:

(1) salivation (S)

(2) lacrimation (L)

(3) urinary frequency (U)

(4) diarrhea (D)

(5) gastrointestinal cramping (G)

(6) emesis (E)

(7) miosis (M)