Munich Score of Meimarakis et al for Predicting Long-Term Survival Following Resection of Pulmonary Metastases of a Renal Cell Carcinoma

Description

Meimarakis et al reported the Munich score for predicting long-term survival after resection of pulmonary metastases from a renal cell carcinoma. This can help to identify a patient who may benefit from more aggressive management. The authors are from Ludwig-Maximilians-Universitat Munchen.

Patient selection: resection of lung metastases from a renal cell carcinoma

Outcome: overall survival in months

Parameters:

(1) R status for the resection of pulmonary metastases)

(2) prognostic factors

(2a) pleural infiltration

(2b) synchronous vs metachronous metastases

(2c) nodal status of the primary tumor

(2d) diameter of the largest metastasis in cm

(2e) metastases to hilar and/or mediastinal lymph nodes

Resection	R status
complete with negative margins	R0
grossly resected but margins positive	R1
other incomplete resections	R2

Prognostic Factor	Finding	Points
pleural infilation	no	0
	yes	1
timing of metastases	synchronous	1
	metasynchronous	0
nodal status of primary tumor	N0	0
	N1	1
diameter of metastasis	< 3 cm	0
	>= 3 cm	1
hilar or mediastinal lymph nodes	negative	0
	positive	1

total number of prognostic factors =

= SUM(points for all 5 prognostic factors)

R status	Number of Prognostic Factors	Risk Group	Median Overall Survival
R0	0	low	90 months
R0	>= 1	intermediate	31 months
R1 or R2	NA	high	14 months

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Munich Score of Meimarakis et al for Predicting Long-Term Survival Following Resection of Pulmonary Metastases of a Renal Cell Carcinoma

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