Rarely the first sign of a pheochromocytoma in a patient may be shock with multi-organ failure (MOF). Emergency surgery can be life saving.
Precipitating event: hemorrhagic necrosis of the tumor with a massive release of catecholamines
Signs and symptoms:
(4) tachycardia with palpitations
(5) pallor with cold extremities
(6) nervousness and/or tremor
(7) acute abdominal pain with or without chest pain
(9) nausea and vomiting
The absence of hypertension is a common reason why the diagnosis is not considered.
Multiple organ failures may include:
(1) renal failure
(2) respiratory failure
(4) lactic acidosis
(5) disseminated intravascular coagulopathy (DIC)
(7) hepatic failure
The patient often is hemodynamically stable and does need vasopressor or inotropic support.
(1) septic shock
(2) stimulant overdose
(3) fulminant viral infection
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Purpose: To evaluate a patient with pheochromocytoma who presents with multiple organ failure (MOF).
Specialty: Endocrinology, Clinical Laboratory, Hematology Oncology
Objective: clinical diagnosis, including family history for genetics, disease progression
ICD-10: D35.0, C74.1,