Description

Multiple Organ Dysfunction Score is intended to offer an objective measure for the severity of multiple organ disorders. Six key organ systems commonly affected in systemic disorders are assessed. A cumulative score correlates with mortality rate seen for the seriously ill patient.


Organ System

Measure

Finding

Score

respiratory

PO2/FIO2 ratio

> 300

0

 

 

226-300

1

 

 

151-225

2

 

 

76-150

3

 

 

<= 75

4

renal

serum creatinine

<= 100 µmol/L

(<=1.1 mg/dL)

0

 

 

101-200 µmol/L

(1.1-2.3 mg/dL)

1

 

 

201-350 µmol/L

(2.3-4.0 mg/dL)

2

 

 

351-500 µmol/L

(4.0-5.7 mg/dL)

3

 

 

> 500 µmol/L

(>5.7 mg/dL)

4

hepatic

serum bilirubin

<= 20 µmol/L

(<= 1.2 mg/dL)

0

 

 

21-60 µmol/L

(1.2-3.5 mg/dL)

1

 

 

61-120 µmol/L

(3.5-7.0 mg/dL)

2

 

 

121-240 µmol/L

(7.0-14.0 mg/dL)

3

 

 

> 240 µmol/L

(> 14.0 mg/dL)

4

cardiovascular

pressure adjusted heart rate (see below)

<= 10.0

0

 

 

10.1-15.0

1

 

 

15.1-20.0

2

 

 

20.1-30.0

3

 

 

> 30.0

4

hematologic

platelet count

> 120,000 /µL

0

 

 

81,000-120,000 /µL

1

 

 

51,000-80,000 /µL

2

 

 

21,000-50,000 /µL

3

 

 

<= 20,000 /µL

4

neurologic

Glasgow coma score

15

0

 

 

13-14

1

 

 

10-12

2

 

 

7-9

3

 

 

<=6

4

 

where:

• conversion factor for creatinine µmol/L to mg/dL is 0.011312

• conversion factor for bilirubin µmol/L to mg/dL is 0.05848

 

Cardiovascular Calculations

 

pressure adjusted heart rate =

= (heart rate in beats per minute) * (right atrial pressure in mm Hg) / (mean arterial pressure in mm Hg)

 

mean arterial pressure =

= ((systolic arterial pressure in mm Hg) + (2 * (diastolic arterial pressure in mm Hg))) / 3

 

Calculation and Interpretation

 

Multiple Organ Dysfunction Score =

= (respiratory points) + (renal points) + (hepatic points) + (cardiovascular points) + (hematologic points) + (neurologic points)

 

Interpretation:

• minimum score: 0

• maximum score: 24

 

Score

ICU Mortality

Hospital Mortality

0

0%

0%

1-4

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