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Multidrug-Resistance Pulmonary Tuberculosis (MDR-TB) Score of Martinez et al

Description

Martinez et al report a clinical prediction rule for evaluating a patient for multidrug-resistant tuberculosis (MDR TB). The authors are from Universidad Peruana Cayetano Heredia (Lima), University of Alabama at Birmingham, Birmingham VA Medical Center and the Peruvian Tuberculosis Program.


Patient selection: Peruvian with AFB in smear, failed therapy or had early relapse

 

Parameters:

(1) history of tuberculosis with failed therapy or early relapse (within 12 months)

(2) multidrug-resistant tuberculosis contact in family

(3) abnormal lung exam

(4) cavitary lesion on chest imaging studies

 

Parameter

Finding

Points

history of TB

no

0

 

yes

3

MDR TB contact

no

0

 

yes

2

abnormal lung exam

no

0

 

yes

-1

cavitary lesion

no

0

 

yes

1

 

total score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: -1

• maximum score: 6

• The higher the score the greater the risk for MDR TB.

 

Score

Risk Group

MDR TB

<= 0

low

3.2%

1 or 2

intermediate

6%

3 to 6

high

42%

 


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